Wednesday, September 5, 2012
Saturday, November 1, 2008
New Biotechnologies tool in Herbal Drug Research
Arvind Kumar, Balkrishna Acharya,and Upadhyay A. K
Department of Ayurved Research & Development, Divya Yog Mandir Trust (SIRO), Office: Patanjali Yogpeeth, Maharishi Dayanand Gram, Delhi Haridwar National Highway, Near Bahadrabad, Haridwar-249402, Uttarakhand, INDIA
arv1069@rediffmail.com
Abstract
Natural products are among the largest and most diverse groups of plant secondary metabolites. Due to heavy demand of natural products many medicinal plant species are presently endangered and their use is prohibited .The application of biotechnological tools can help to protect the endangered species by understanding the molecular mechanisms of the synthesis of therapeutically active principles of medicinal plants. Conventional strategies for expression profiling are optimized for single gene analysis but SOLiD System has the potential to deliver real breakthroughs in any application of sequencing aimed at understanding biological functions in complex genomes. We proposed to use ‘Supported Oligo Ligation Detection’ to identify the responsible gene responsible for active compound synthesis in endangered medicinal plants. Once the responsible gene is evaluated using SOLiD, the phylogenetic reconstruction studies are primarily done by inserting the basic gene responsible for active compounds synthesis into a specific vector to produce a recombinant system. This recombinant system is inserted into host system for development of transgenic plants that will secure the overproduction of active compounds synthesis. Other major practical applicability of research is pharmacodynamics, pharmacogenomics, toxicogenomics and quality control of herbal drugs and extracts.
Department of Ayurved Research & Development, Divya Yog Mandir Trust (SIRO), Office: Patanjali Yogpeeth, Maharishi Dayanand Gram, Delhi Haridwar National Highway, Near Bahadrabad, Haridwar-249402, Uttarakhand, INDIA
arv1069@rediffmail.com
Abstract
Natural products are among the largest and most diverse groups of plant secondary metabolites. Due to heavy demand of natural products many medicinal plant species are presently endangered and their use is prohibited .The application of biotechnological tools can help to protect the endangered species by understanding the molecular mechanisms of the synthesis of therapeutically active principles of medicinal plants. Conventional strategies for expression profiling are optimized for single gene analysis but SOLiD System has the potential to deliver real breakthroughs in any application of sequencing aimed at understanding biological functions in complex genomes. We proposed to use ‘Supported Oligo Ligation Detection’ to identify the responsible gene responsible for active compound synthesis in endangered medicinal plants. Once the responsible gene is evaluated using SOLiD, the phylogenetic reconstruction studies are primarily done by inserting the basic gene responsible for active compounds synthesis into a specific vector to produce a recombinant system. This recombinant system is inserted into host system for development of transgenic plants that will secure the overproduction of active compounds synthesis. Other major practical applicability of research is pharmacodynamics, pharmacogenomics, toxicogenomics and quality control of herbal drugs and extracts.
Tuesday, October 21, 2008
Study and evaluation of some lesser known herbs potentially used as folk medicine by Jaunsari tribe
Upadhyay A.K. 1 & Kaushal Kumar. 2
1Department of Ayurved Research & Development, DYMT (SIROs), Patanjali Yogpeeth, Haridwar-249402
2Patanjali Herbal Garden & Agro Research Deptt., DYMT (SIROs), Patanjali Yogpeeth, Haridwar-249402
ABSTRACT
The present communication reports about some potential plants used as tribal medicine of Jaunsari for the treatment of various diseases and disorders. The Jaunsari tribe of Jaunsar-Bawar is a primitive group of people who have their own culture, custom and traditions. They are living in close vicinity of Himalayan and Shivalik region which is rich in plant wealth and ambient vegetation. They are residing close to nature and use a number of wild plants such as Aesculus indica, Asparagus filicinus, Berberis chitria, Bidens biternata, Cannabis sativa, Cinnamomum tamala, Cissampelos pareira, Crotalaria spectabilis, Cryptolepis buchananii, Datura stramonium, Oxalis corniculata, Rumex nepalensis, Solanum ferox, Thalictrum foliolosum, Viola canescens, Zanthoxylum armatum etc. for primary healthcare. There are not any initiations undertaken regarding the exploration of lesser known uses of medicinal plants in perspectives of Ayurveda. There are ample scopes in Dravya guna of Ayurveda where many other important interesting medicinal plants especially used by tribes, may be introduced which have not been earlier mentioned in anywhere in classical text of India. The present study has greater significance towards the development of healthcare products based on lesser known potential plants of ethnomedicinal leads/oral wisdom of Jaunsari tribe. The study has greater significance to enrichment the Dravyaguna/Ayurvedic pharmacopoeia and maintaining continuation to addition of specific and new plants in Ayurveda.
Keywords: Lesser known herbs, Folk Medicine, Jaunsari Tribe, Ethnomedicine, Ayurveda
1Department of Ayurved Research & Development, DYMT (SIROs), Patanjali Yogpeeth, Haridwar-249402
2Patanjali Herbal Garden & Agro Research Deptt., DYMT (SIROs), Patanjali Yogpeeth, Haridwar-249402
ABSTRACT
The present communication reports about some potential plants used as tribal medicine of Jaunsari for the treatment of various diseases and disorders. The Jaunsari tribe of Jaunsar-Bawar is a primitive group of people who have their own culture, custom and traditions. They are living in close vicinity of Himalayan and Shivalik region which is rich in plant wealth and ambient vegetation. They are residing close to nature and use a number of wild plants such as Aesculus indica, Asparagus filicinus, Berberis chitria, Bidens biternata, Cannabis sativa, Cinnamomum tamala, Cissampelos pareira, Crotalaria spectabilis, Cryptolepis buchananii, Datura stramonium, Oxalis corniculata, Rumex nepalensis, Solanum ferox, Thalictrum foliolosum, Viola canescens, Zanthoxylum armatum etc. for primary healthcare. There are not any initiations undertaken regarding the exploration of lesser known uses of medicinal plants in perspectives of Ayurveda. There are ample scopes in Dravya guna of Ayurveda where many other important interesting medicinal plants especially used by tribes, may be introduced which have not been earlier mentioned in anywhere in classical text of India. The present study has greater significance towards the development of healthcare products based on lesser known potential plants of ethnomedicinal leads/oral wisdom of Jaunsari tribe. The study has greater significance to enrichment the Dravyaguna/Ayurvedic pharmacopoeia and maintaining continuation to addition of specific and new plants in Ayurveda.
Keywords: Lesser known herbs, Folk Medicine, Jaunsari Tribe, Ethnomedicine, Ayurveda
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